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Syrian Republican Guard major general Issam Zahreddine, known for leading battles against the rebels in Homs and Aleppo, is killed by a landmine in Deir ez-Zor, according to Syrian media.
2017-10-18

Russian and Syrian government attacks on rebel-held east Aleppo kill two people and injure 13 others. The Syrian American Medical Society reports the city's main trauma hospital closes.
2016-10-1

Syrian Government forces capture the main road into the parts of Aleppo controlled by rebels.
2016-07-17

Syrian government airstrikes hit rebel-held areas in Aleppo, killing at least 34 people.
2016-06-15

Islamic State fighters take control of a section of road running between the towns of Khanaser and Ithriya, southeast of Aleppo, according to a monitoring group. This threatens the Syrian army's only supply route into the city.
2015-10-23

Russian warplanes bomb Islamic State positions in the central Syrian city of Palmyra and in the northern Aleppo province, releasing videos that show them destroying 20 vehicles and 3 weapons depots.
2015-10-6

A large explosion levels the Carlton Hotel in Aleppo which was used as a military base by the Army of Syria as well as several other buildings.
2014-05-8

Rebel forces seize parts of the Sheikh Suleiman army base near Aleppo after weeks of heavy fighting. Ground clashes continue in the suburbs of Damascus as the government carries out further air raids against opposition forces.
2012-12-10

Syrian civil war: Rebels claim control of the strategic town of Maarrat al-Nu'man on the main road linking Damascus to Aleppo.
2012-10-10

The Syrian Army increases artillery shelling of Aleppo as the Free Syrian Army tries to consolidate its control of the city's eastern districts.
2012-08-3