The United States Department of Defense reports that forces have killed a senior al-Qaeda leader in Syria through an MQ-9 drone strike.
Chinese Minister for Foreign Affairs Wang Yi asks the Taliban during a conference in Dushanbe, Tajikistan, to make a "clean break" with all terrorist forces, especially the al-Qaeda-backed East Turkestan Islamic Movement, and to return to mainstream Afghan politics.
Abu Bakr al-Baghdadi, leader of the Islamic State of Iraq and the Levant, is believed to have died in a suicide bombing after U.S.-led coalition special forces raid targeted positions belonging to Huras al-Din in Syria's rebel-held Idlib Governorate. U.S. President Donald Trump makes a statement at 9:00 AM EDT (1300 UTC) asserting his death.
Médecins Sans Frontières reports that an air strike has destroyed a hospital in the Idlib Governorate of northwest Syria, with seven people killed and at least eight people missing, presumed to be dead.
Russian airstrikes on an Al-Nusra Front (Al-Qaeda's branch in Syria)-run prison complex in the northern town of Maarrat al-Nu'man, Idlib, leaves nearly 60 people dead. Most of those killed were rebels imprisoned by Al-Nusra, according to the Syrian Observatory for Human Rights.
The Syrian Observatory for Human Rights reports Russian airstrikes kill at least 18 civilians and wound dozens more in the town of Ariha in Syria's northwestern Idlib province. Idlib is controlled by the Army of Conquest, a rebel alliance of mainly Islamist groups, including al-Qaeda affiliate al-Nusra Front.
The Russian military launches cruise missile strikes from the Mediterranean on ISIS positions in Al-Raqqah, the Islamic State of Iraq and the Levant's de facto capital in Syria, Aleppo, and Idlib. A U.S. official confirms that Russia has conducted a significant number of strikes in Syria using both sea-launched cruise missiles and long-range bombers. Russian President Vladimir Putin has pledged to escalate his military campaign in Syria after it was confirmed that a bomb brought down Metrojet Flight 9268 over Egypt's Sinai Peninsula.
Russian air-strikes reportedly kill U.S.-backed Syrian rebels as Russian jets bomb rebel positions in rural areas of northern Syria, including the town of Jisr al-Shughour, which is currently held by Islamist militant groups including Al-Qaeda's branch in Syria, the Al-Nusra Front.
Islamist rebels including the al-Qaeda-affiliated al-Nusra Front claim to have captured most of the town of Jisr al-Shughur in the Idlib Governorate.
Syrian officers reports that Syrian Army kills senior Saudi Arabian al-Qaeda commander Abu Malik al-Shahri, who is known as 'Bin Laden of Syria', in outskirt of Latakia.