The Syrian Deputy Foreign Minister, Faisal Mekdad, blames the Turkish offensive on the Kurdish forces, saying Syria will not be negotiating with them "on the terms of separatism".
The death toll since February 18 in the rebel-held Damascus suburb of Eastern Ghouta is more than 400, according to the Syrian Observatory for Human Rights.
United Nations High Commissioner for Human Rights Zeid bin Ra'ad calls on all air forces in Syria to better distinguish between military targets and civilians.
The Syrian Observatory for Human Rights says the death toll from an airstrike on an IS-controlled eastern city near the border with Iraq rose from 25 to 71.
Rebels kill 18 soldiers in Idlib Governorate in a car bomb and ground attack on a military installation.