North Macedonian Prime Minister North Macedonian Prime Minister Zoran Zaev announces his resignation following a decisive defeat of his party, the Social Democratic Union, in the local elections.
October 2021 Sudanese coup d'état Sudanese Prime Minister Abdalla Hamdok says that he will not step down despite being under house arrest following the military coup.
2021 Japanese general election Japanese citizens head to the polls to elect members of the Lower House. The ruling Liberal Democratic Party faces more opposition than in previous elections due to the handling of the COVID-19 pandemic in the country.
Mexican National Guard The Mexican National Guard open fire against a vehicle carrying Cuban citizens, killing one person and wounding four more people. The guards said that "the vehicle didn't stopped when ordered to do so".
October 2021 Tokyo attack A man attacks passengers on a train in Chōfu, Tokyo, Japan, with acid and a knife, before setting the train on fire, injuring 17 people. A man is arrested at the scene.
India Indian Prime Minister Narendra Modi visits Pope Francis in the Vatican. It is the first-ever meeting between the two leaders. Modi is in Rome for the G20 Heads of State and Government Summit, October 30-31, before he flies to Glasgow, Scotland, for the 26th United Nations Conference on Climate Change (COP26), October 31 to November 12.
COVID-19 pandemic White House Press Secretary Jen Psaki says that she has tested positive for COVID-19 following a meeting with President Joe Biden. She said in a statement that she is experiencing mild symptoms.
Russia reports a record for the second consecutive day of 40,993 new cases of COVID-19, thereby bringing the nationwide total of confirmed cases to 8.51 million.
The United Arab Emirates issues an emergency use authorization of the Pfizer–BioNTech COVID-19 vaccine for children aged 5 to 11.
Firefighter Nine firefighters are killed during a training exercise inside a cave in Altinópolis, São Paulo, Brazil, after the roof of the cave collapsed.
Pemex One person is killed and 15 others are injured when a Pemex gas pipeline explodes in Puebla, Mexico. The Governor of Puebla, Miguel Barbosa Huerta, blames an illegal tap for the explosion.
2021 Salisbury rail crash Seventeen people are injured in a derailment and crash between two trains near Salisbury, Wiltshire, England.
Insurgency in the Maghreb Gunmen open fire against security forces in Sourou, Burkina Faso, killing five policemen. Fifteen attackers are killed in a gunfight after the attack.
Yemeni Civil War Two missiles are launched against a mosque in Marib Governorate, killing and wounding a total of 29 people.